In contrast, it does not bind to the androgen receptor.
It appears to do so by stimulating androgen receptors in the brain.
It acts on androgen receptors in responsive tissue throughout the body.
Significantly, the altered males still have all their androgen receptors intact.
More recently, androgen receptors have been shown to have a second mode of action.
Androphilic is also sometimes used to describe certain proteins and androgen receptors.
This effect is caused by the ability of some progestins to inhibit androgen receptors.
Thus, changes in levels of specific proteins in cells is one way that androgen receptors control cell behavior.
Higher androgen levels lead to increased expression of androgen receptor.
In addition, bicalutamide accelerates the degradation of the androgen receptor.