Jeff Gray pitched the last two innings.
Clemens, who has lost just five times, struck out eight and didn't issue a walk before giving way to Jeff Gray at the start of the eighth.
Cleveland scored a run in the bottom of the ninth when Jeff Gray threw a wild pitch with runners at second and third.
Toronto put the game away against Jeff Gray and Tom Bolton in the eighth.
However, while waiting for execution, two men named James Bower and Jeff Gray confessed to the murders.
"Appearances were very important," said Jeff Gray, a former economist at Enron Energy Services.
Toronto would enjoy yet another three-run inning, in the seventh, picking on Jeff Gray this time.
Dana Kiecker and Jeff Gray combined to win by 2-0 Friday night.
Jeff Gray got the last two outs in the top of the 10th for the victory in his first major league decision.
Andersen was touched for one run before giving way to Jeff Gray, who pitched a scoreless ninth.