In addition, a gap in the protein is accessible directly from the hydrophobic core of the inner leaflet of the membrane bilayer.

Thus, C1P reside in the organelle where it was formed and is unlikely to spontaneously flip-flop across membrane bilayers.

Their amino acid composition, amphipathicity, cationic charge and size allow them to attach to and insert into membrane bilayers to form pores by 'barrel-stave', 'carpet' or 'toroidal-pore'

When platelets are activated, negatively charged phospholipids move from the inner to the outer leaflet of the membrane bilayer.

They are not stored in vesicles, and exist as integral constituents of the membrane bilayers that make up cells.

The interaction of integral proteins with the lipids inside membrane bilayer is of great importance for membrane function.

Bacteria regulate membrane fluidity by manipulating the relative levels of saturated and unsaturated fatty acids within the phospholipids of their membrane bilayers.

Lipid rafts are more ordered and tightly packed than the surrounding bilayer, but float freely in the membrane bilayer.

The membrane-spanning region of the ABC transporter protects hydrophilic substrates from the lipids of the membrane bilayer thus providing a pathway across the cell membrane.

Saccharolipids describe compounds in which fatty acids are linked directly to a sugar backbone, forming structures that are compatible with membrane bilayers.