Drug use in the first trimester is the most harmful to the fetus in terms of neurological and developmental outcome.
Combined therapies of hypothermia and pharmacological agents or growth factors to improve neurological outcomes are most likely the next direction for damaged neonatal brains, such as after a stroke.
Taken together these data link neurological outcome in early treated subjects closely to the quality of phenylalanine control throughout life.
Such therapy has been shown to improve neurological outcome and reduce death.
Longer episodes of PTA, especially those longer than four weeks, are associated with worse cognitive, neurological and functional outcomes.
This position for tPA is based upon the findings of two studies by one group of investigators which showed that tPA improves the chances for a good neurological outcome.
"The relationship of the neuro-endorcrine axis to neurological outcome in infants less than 30 weeks gestation".
The 66 minutes Michelle spent in the creek was "the longest documented submersion with an intact neurological outcome," said an editorial accompanying the report in the July 15 issue of the journal.
Strong evidence links pesticide exposure to worsened neurological outcomes.
There is no current evidence of significant survival benefit with improved neurological outcomes in patients given combinations of both epinephrine and vasopressin during cardiac arrest.