No normal children have been born and all adults have met their end through despair.
"I remember these figures precisely, because I have had to learn them through great despair and difficulty."
Through our panic and despair, an order became a duty.
Millions of young people were going through the same agony and despair all over China.
Captain Ryan and his men, having been through such despair before, were less troubled by the news.
Here we have Sullivan's real subject - his way back to faith through anger and despair.
By eight o'clock, soaked through and in despair, I ended up back at the apartment.
"I been through despair before, an' I didn't like it."
Their strength grows through despair and they focus on one racial group that is easy prey.
It was impossible to tell how they had died, but it may have been through despair.