The European Union has also approved Optaflu, a vaccine produced by Novartis using vats of animal cells.
To collect insulin on an industrial scale is the same principle but just uses huge vats and pipes instead.
A very few breweries still use wooden vats for fermentation but wood is difficult to keep clean and infection-free and must be repitched more or less yearly.
Törley currently produces sparkling wine using both the méthode traditionelle of in-bottle fermentation as well as the Charmat process which uses large vats for the second fermentation.
Known as "The Vats," the brewery was a center of San Francisco punk rock culture with about 200 bands using individual vats as music studios.
In the letter, he claimed to have strangled and dismembered the victims - mostly runaways and orphans living on the streets of Lahore - and disposed of their bodies using vats of hydrochloric acid.
The alternative method of producing shikimic acid developed by Professor Frost involves fermentation using vats of genetically engineered bacteria.
They use vats filled with cooking oil that is heated by gas flames from shielded burners.
Shoe polish can be manufactured using large vats, reasonably powerful heaters and air conditioners.