Additional examples are adjusted to the entries in an automated way - we cannot guarantee that they are correct.
Most fatalities are not verified but those which are involve excessive doses or coingestion with other drugs.
Delirium and lactic acidosis caused by ethanol and niacin coingestion.
Benzodiazepine overdoses can be much more dangerous if a coingestion of other CNS depressants such as opiates or alcohol has occurred.
Only a fraction of the handful of cases reviewed for liver toxicity could be, with any certainty, linked to kava consumption and most of those involved the coingestion of other medications/supplements.