event of cosmic significance

Altdorfer saw the Battle of Issus as a principal indicator of the transition of power from Persia to Greece, and thus as an event of cosmic significance.

Apostle Paul viewed the birth of Jesus as an event of cosmic significance which brought forth a "new man" who undid the damage caused by the fall of the first man, Adam.

I felt again the sensation of being present at some event of cosmic significance, on that bright day in that remote place; yet I have been present at several significant moments in history without any such mysterious intimations at all.