fundamentally disagree
profoundly disagree

Then, still fundamentally disagreeing about how to achieve these goals, they flew off again, without committing themselves to anything likely to make any real difference.

Commercial colleagues may likewise fundamentally disagree with the views of the paper and its writers.

And we disagree fundamentally on the future of this state.

I have been asked to present an argument with which I fundamentally disagree.

"How can we disagree fundamentally when we love each other?"

Ladies and gentlemen, I disagree fundamentally with that assessment of the situation.

However, there are a number of paragraphs that we fundamentally disagree with.

The report is also brimming with a great many other points with which I fundamentally disagree.

You know very well what I said: that, indeed, we fundamentally disagree with this kind of system and, therefore, it should be reviewed.

I fundamentally disagree with Government simply doling out free aid to developing countries.