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Genetic hitchhiking occurs when one allele is strongly selected for and driven to fixation.
Additionally, they found that substitutions in slowly evolving genes were associated with stronger genetic hitchhiking effects.
This phenomenon is called genetic hitchhiking.
They focused on Drosophila melanogaster population data and the effects of genetic hitchhiking caused by selective sweeps.
Recombination counteracts physical linkage between adjacent genes, thereby reducing genetic hitchhiking.
Both genetic hitchhiking and background selection are stochastic (random) evolutionary forces, like genetic drift.
Mechanisms that can lead to changes in allele frequencies include natural selection, genetic drift, genetic hitchhiking, mutation and gene flow.
Recombination can interrupt the process of genetic hitchhiking, ending it before the hitchhiking neutral or deleterious allele becomes fixed or goes extinct.
Other alternative theories propose that genetic drift is dwarfed by other stochastic forces in evolution, such as genetic hitchhiking, also known as genetic draft.
Genetic hitchhiking can cause neutral mutations to have sojourn times proportional to log(N): this may explain the relationship between measured effective population size and the local recombination rate.
A neutral mutation that is in linkage disequilibrium with other alleles that are under selection may proceed to loss or fixation via genetic hitchhiking and/or background selection.
On a population level, processes that influence linkage disequilibrium include genetic linkage, epistatic natural selection, rate of recombination, mutation, genetic drift, random mating, genetic hitchhiking and gene flow.
These are alleles that are normally rare in both species but, probably due to genetic hitchhiking on genes for hybrid fitness, reach high frequencies in the areas where most hybrids are formed.
When a population is expanding geographically, genetic hitchhiking can be intensified at the invasive species front, where adaptive alleles get a double advantage: they are adaptive, and they also arrive first in new territories.
The name emphasizes the fact that the genetic background, or environment, of a neutral mutation has a significant impact on whether it will be preserved (genetic hitchhiking) or purged (background selection) from a population.
Recombination breaks up this linkage disequilibrium too slowly to avoid genetic hitchhiking, where an allele at one locus rises to high frequency because it is linked to an allele under selection at a nearby locus.
This test is an advancement over Tajima's D, which is used to differentiate neutrally evolving sequences from those evolving non-randomly (through directional selection or balancing selection, demographic expansion or contraction or genetic hitchhiking).
It appears then, that a novel genotype emerged containing this form of Chr1a and swept the entire European and North American population of Toxoplasma gondii, bringing with it the rest of its genome via genetic hitchhiking.
Genetic hitchhiking has therefore been viewed as a major challenge to neutral theory, and an explanation for why genome-wide versions of the McDonald-Kreitman test appear to indicate a high proportion of mutations becoming fixed for reasons connected to selection.
Genetic hitchhiking, also called genetic draft or the hitchhiking effect, is when an allele changes frequency not because it itself is under natural selection, but because it is near another gene on the same chromosome that is undergoing a selective sweep.
A second hypothesis of the neutral theory is that most evolutionary change is the result of genetic drift acting on neutral alleles, rather than for example genetic hitchhiking of a neutral allele due to genetic linkage with non-neutral alleles.
This finding suggests that reassortment between segments occurs slowly enough, relative to the actions of positive selection, that genetic hitchhiking causes beneficial mutations in HA and NA to reduce diversity in linked neutral variation in other segments of the genome.
This can be important when one allele in a particular haplotype is strongly beneficial: natural selection can drive a selective sweep that will also cause the other alleles in the haplotype to become more common in the population; this effect is called genetic hitchhiking or genetic draft.
Originally considered to be caused by elevated rates of mutation in hybrids, they are now believed to be the result of purifying selection: in the centre of the hybrid zone, alleles for hybrid fitness are selected, and linked alleles also increase in frequency by genetic hitchhiking.
Genetic draft is the effect on a locus by selection on linked loci.
The mathematical properties of genetic draft are different from those of genetic drift.
Genetic draft generates a different allele frequency spectrum to genetic drift.
One important alternative source of stochasticity, perhaps more important than genetic drift, is genetic draft.
Evolutionary forces include natural selection, sexual selection, genetic drift, genetic draft, developmental constraints, mutation bias and biogeography.
Genetic draft results in similar behavior to the equation above, but with an effective population size that may have no relationship to the actual number of individuals in the population.
John H. Gillespie credits Provine with stimulating his interest in the topic of hitchhiking or "genetic draft" as an alternative to genetic drift.
Other alternative theories propose that genetic drift is dwarfed by other stochastic forces in evolution, such as genetic hitchhiking, also known as genetic draft.
Genetic draft caused by the fact that some neutral genes are genetically linked to others that are under selection can be partially captured by an appropriate effective population size.
Both genetic drift and genetic draft are random evolutionary processes, i.e. they act stochastically and in a way that is not correlated with selection at the gene in question.
This discussion is intended to provide a forum for historians, philosophers, and biologists to explore the idea of GENETIC DRAFT.
Stochasticity associated with linkage to other genes that are under selection is not the same as sampling error, and is sometimes known as genetic draft in order to distinguish it from genetic drift.
This could happen through an increase in the census population size, decreasing genetic drift, through an increase in the recombination rate, decreasing genetic draft, or through changes in the probability distribution of the numbers of offspring.
In particular, I will consider the processes of genetic drift, stochastic fluctuations in gene frequencies due to finite population size, and genetic draft, stochastic fluctuations in gene frequencies due to linkage to positively selected mutations.
Genetic hitchhiking, also called genetic draft or the hitchhiking effect, is when an allele changes frequency not because it itself is under natural selection, but because it is near another gene on the same chromosome that is undergoing a selective sweep.
Instead of sitting through videotape of hundreds of high school football, basketball or baseball games every year looking for a promising rookie, will these legends of the sports world be replaced by clerks who go online and scan a lab's data bank for genetic draft picks?
Changes in the frequency of an allele in a population are mainly influenced by natural selection, where a given allele provides a selective or reproductive advantage to the organism, as well as other factors such as mutation, genetic drift, genetic draft, artificial selection and migration.
This discussion of the nature of genetic draft and its significance for molecular evolution extends and records a discussion begun as part of the Dibner MBL Seminar on the History of Molecular Evolution on May 22 and 23, 2004.
This can be important when one allele in a particular haplotype is strongly beneficial: natural selection can drive a selective sweep that will also cause the other alleles in the haplotype to become more common in the population; this effect is called genetic hitchhiking or genetic draft.
Genetic hitchhiking, also called genetic draft or the hitchhiking effect, is when an allele changes frequency not because it itself is under natural selection, but because it is near another gene on the same chromosome that is undergoing a selective sweep.
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