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Water for mice in gnotobiotic isolators must be sterile.
Gnotobiotic animals are bred in isolators and their microbiological flora is known.
With a series of experiments using gnotobiotic mice, Faith et al. demonstrated that it is possible to predict changes in the human gut microbiota.
Stimulation of intestinal immune cells by E. coli in gnotobiotic piglets.
Animals reared in a gnotobiotic colony often have poorly developed immune systems, lower cardiac output, thin intestinal walls and high susceptibility to infectious pathogens.
A gnotobiotic animal (from Greek roots gnostos 'known' and bios 'life') is an animal in which only certain known strains of bacteria and other microorganisms are present.
They were all of them - even the colonists down in the hyb tanks - expendable biopsy material, Doppelgangers grown in gnotobiotic sterility in the Moonbase.
Lorenz A, Schulze J. Establishment of E. coli Nissle 1917 and its interaction with Candida albicans in gnotobiotic rats.
They had a gnotobiotic atmosphere, a little rich in oxygen, a little more humid than the ambient air, plus pressure to help their weak metabolism keep oxygen spread in their parts.
Isolation of swine infertility and respiratory syndrome virus (isolate ATCC VR-2332) in North America and experimental reproduction of the disease in gnotobiotic pigs.
To tease apart the complex relationships that exist within this gut micobiota, Dr. Gordon's research program employs germ-free and gnotobiotic mice as model hosts, which may be colonized with defined, simplified microbial communities.
In other study, researchers introduce a human microbiota in gnotobiotic mice in order to compare the different changes for developing new ways to manipulate the properties of the microbiota so as to prevent or treat various diseases.
When known strains of bacteria or microbiota are introduced to a germ-free animal, it usually referred to as a gnotobiotic animal, however technically speaking, germ-free animals are also gnotibiotic because the status of their microbial community is known.
Gnotobiotic animals (also 'gnotobiotes' or 'gnotobionts') are born in aseptic conditions, which may include removal from the mother by Caesarean section and immediate transfer of the newborn to an isolator where all incoming air, food and water is sterilized.