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As early as 1944, Fermi tested the world's first liquid-fuel reactor in Chicago.
Liquid-fuel reactors offer significant safety advantages due to their inherently stable "self-adjusting" reactor dynamics.
Chemical engineers hoped to design liquid-fuel reactors that would dispense with the costly destruction and processing of solid fuel elements.
Enrico Fermi advocated construction at Los Alamos of what was to become the world's third reactor, the first homogeneous liquid-fuel reactor, and the first reactor to be fueled by uranium enriched in uranium-235.