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The Nestorian and Monophysite schisms of the 5th century divided the church into separate denominations.
There is no doubt that Lavigerie's initial aim was to Christianize the Arab peoples, and thus begin to reverse the ravages introduced by the Monophysite schism over 1300 years before.
Justinian entered the arena of ecclesiastical statecraft shortly after his uncle's accession in 518, and put an end to the Monophysite schism that had prevailed between Rome and Constantinople since 483.
The Armenian calendar uses the calendar era of AD 552, reflecting the separation of the Armenian Apostolic Church from the Roman Church due to the Monophysite schism.
This liturgy was used throughout Syria and Palestine, that is throughout the Antiochene Patriarchate (Jerusalem was not made a patriarchal see till the Council of Ephesus, 431) before the Nestorian and Monophysite schisms.
After the Monophysite schism and the Council of Chalcedon (451), The Greek Orthodox Patriarchate of Antioch, the proto-Maronites (Syriac Melkites) and the Syriac Orthodox Church continued using the same rite.
Erasmus was saying, for the disputes which led to Arianism, to the Monophysite schism and to Islam, and so much for the fatal word which had divided East and West since 1054 and had lost Byzantium to the Christian world.
In the seventh century, the doctrinal errors which had led to the Monophysite schism finally came home to roost: the whole enormous area where Monophysite belief was dominant succumbed with great speed to the new Islamic version, which not only engulfed these territories but swept along the coast of North Africa and into Spain.