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Statistically, the experimental procedure was non-inferior to the standard practice.
It's a non-inferiority trial and there's a certain band of what would be considered non-inferior.
It may not be possible to establish the safety and efficacy of an experimental treatment with a non-inferior active control trial.
Cure rates for tigecycline were shown to be non-inferior to the comparators.
Menactra™ was found to be immunologically non-inferior to Menomune® in a randomized control trial that enrolled 2,554 adults 18 to 55 years of age.
Post-meal administration was demonstrated to be non-inferior to regular insulin administered 30-45 minutes prior to a meal.
They provide some peace of mind, and the scenario that Xarelto is only non-inferior to warfarin can be discarded."
The once-daily regimen was determined to be non-inferior to the twice-daily regimen.
The study met its primary endpoint, demonstrating that panitumumab was non-inferior to cetuximab for overall survival.
Post-meal administration of insulin glulisine also was demonstrated to be non-inferior to pre-meal administration.
The study also comfortably met the main secondary endpoint by demonstrating that naproxcinod was statistically non-inferior to the older drug naproxen.
Cubicin® was found to be non-inferior to the comparator at Test-of-Cure, assessed at 6 weeks post-treatment.
The aim of the study was to demonstrate that pantoprazole-Mg was non-inferior to pantoprazole-Na, the commercial formulation.
Administration of Mircera once a month, was shown to be non-inferior to the comparator drug in maintaining hemoglobin concentrations in the study target range.
Pradax was found to be non-inferior to enoxaprin in total VTE and all-cause mortality.
The data in this submission confirm that pantoprazole-Mg is non-inferior to pantoprazole-Na in healing reflux disease.
The reduction in serum phosphate levels of sucroferric oxyhydroxide-treated patients was non-inferior to that in sevelamer-treated patients.
Isuvaconazole was found to be non-inferior to voriconazole, another triazole antifungal, with all cause mortality at 18.6%, compared to 20.2% in the voriconazole group.
However, pantoprazole magnesium was found to be non-inferior in healing reflux disease and had a comparable safety profile relative to pantoprazole sodium.
A few studies indicate that bivalirudin is non-inferior compared to heparin and that bivalirudin is associated with a lower rate of bleeding.
However, a recent randomized controlled trial found Pneumatic Dilation to be non-inferior to Laparoscopic Heller's Myotomy.
With respect to endoscopic healing after 4 and 8 weeks of treatment in GERD patients, pantoprazole-Mg was found to be non-inferior to pantoprazole-Na.
In 2009, ceftaroline had completed phase-III clinical trials for community-acquired pneumonia comparing it against ceftriaxone with non-inferior results and similar adverse reaction profile.
A trial comparing closure against warfarin therapy found closure to be non-inferior when measured against a composite end point of stroke, cardiovascular death and systemic embolism.
At 96 weeks, the study showed PREZISTA/r was non-inferior to lopinavir/r for virologic response.
Additional noninferior solutions were generated to improve the achievement levels of the initial preferred solution.
Ciprodex was noninferior to competitive products such as Cortisportin and ofloxacin.
Endeavor patients just missed being within the range of scar tissue accumulation that regulators had agreed would be "noninferior."
It has been shown to be statistically noninferior to the combination of vancomycin and ceftazidime for the treatment of skin and soft tissue infections.
However, pantoprazole magnesium was found to be noninferior in healing reflux disease and had a comparable safety profile relative to pantoprazole sodium.
A short course of tedizolid phosphate was statistically noninferior to a 10-day course of linezolid for both early and sustained clinical responses in patients with ABSSSIs.
A solution is called nondominated, Pareto optimal, Pareto efficient or noninferior, if none of the objective functions can be improved in value without degrading some of the other objective values.
That okay was based on the EINSTEIN DVT trial, which showed that rivaroxaban was noninferior to enoxaparin plus warfarin for preventing recurrent deep vein thrombosis.
Six noninferior solution sets that included four goals, total volume harvested, total discounted cash flow, total undiscounted cash flow, and total discounted costs, were generated using a complementary linear and goal programming approach.
Although other combinations of drugs have occasionally been shown to be noninferior at various endpoints and in some subgroups of patients, the combination of cisplatin or carboplatin plus etoposide or irinotecan are considered comparable first-line regimens for SCLC.
An analyst at Lehman Brothers, Jim Birchenough, said in a note yesterday that trying to win approval of Xyotax based on its being "noninferior," in the parlance of the F.D.A., to paclitaxel would be risky because the agency had not agreed to this in advance.
In a 48 week study comparing elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil to elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (trade name Genvoya), the results showed the newer drug to be noninferior to the established agent, but at much lower dosages and with lower incidence of adverse side effects such as impaired kidney function.
A larger, randomized trial designed to determine whether survival using IAD is noninferior to CAD could not rule out a 20% higher relative risk of death using intermittent therapy.
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