of fundamental importance formal
of great account formal
of great consequence formal
of prime importance formal
of substance formal
of the first magnitude formal

But some matter of substance he can come to you with.

At any rate, he soon became a man of substance.

The police did not say what type of substance was involved.

Heat is a form of energy and not a physical substance.

Some of the white substance fell on to the floor.

In fact, they come not from the world, being of the same substance as the stars.

Not a single idea of substance from either party that might help people back into work.

And this is your best chance to feel like a person of substance.

It was the first thing of substance he could remember.

If you want to speak to make a point of substance, go ahead.