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These purposes might differ significantly and may change over time.

The mean age of death is 12 years, although the different forms differ significantly.

A few species differ significantly in appearance from most of the family.

However, it is not known if they differ significantly from each other.

The population and area of the three countries differ significantly.

His back story differs significantly from that of the video game.

Then, when they differ significantly, we would need to consider them different.

The opinions of those who have considered the problem differ significantly.

Each version of the game differs significantly from the others.

However the effect on business differs significantly by between stores.