self-destruction
self-annihilation

Hope they do not blame men for this self destruction.

Wouldn't be surprised if the idea drove him to self destruction.

That's where the human race started its long and tragic history toward self destruction.

Now, with the powder marks on his hand to indicate self destruction, that meant little or nothing.

How the Bakori induced the self destruction was not important.

It was not a large worry, however - for everyone would have to accept the fact of Burdon's self destruction.

Soon afterwards, Ambassador Hell returned to the base, only to die in its self destruction.

Perhaps a time-detonator had arrived at the instant for self destruction at just this moment.

If inclusions are not eliminated by self destruction during the tempering process, in rare cases they may lead to failure at a later time.

It strikes me this is just the inevitable self destruction of a doomed system that is failing throughout the world.