sonophoresis

Sonophoresis is also used without drug delivery in physical therapy, and as a complementary modality for iontophoresis.

Phonophoresis, also known as sonophoresis, is the use of ultrasound to enhance the delivery of topically applied drugs.

Transdermal delivery (sonophoresis) is enhanced through LFUS, which then further allows the drug to be released.

Sonophoresis occurs because ultrasound waves stimulate micro-vibrations within the skin epidermis and increase the overall kinetic energy of molecules making up topical agents.

Sonophoresis is a process that exponentially increases the absorption of semisolid topical compounds (transdermal delivery) into the epidermis, dermis and skin appendages.

Cygnus is also developing transdermal systems based on sonophoresis, which uses ultrasound to move drug molecules through the skin, and electroporation, which uses electrical currents to alter the skin's permeability temporarily.

He has developed ultrasound devices that can be placed on the skin to increase its porosity, thus allowing for the administration of vaccines (sonophoresis), and needle-free jet devices for the direct administration of medicines (liquid jet injector).