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Dolasetron injection can increase the risk of developing torsade de pointes, a potentially fatal abnormal heart rhythm.
When the QT interval is longer than normal, it increases the risk for "torsade de pointes," a life-threatening form of ventricular tachycardia.
Due to the narrow therapeutic index of flecainide, physicians should be alert for signs of toxicity before life-threatening arrhythmias occur like torsade de pointes.
Antiarrhythmic agents (classes Ia and III), phenothiazines and other antipsychotics increase the risk of torsade de pointes due to hypokalemia.
Not recommended: Combinations with lithium, potassium-sparing diuretics, potassium (salts), antiarrhythmic drugs which cause torsade de pointes, anesthetic drugs, cytostatic or immunosuppressive agents.
As Qwilleran and Polly drove back to Indian Village, she said, "Mr. Delacamp is visiting Maggie tomorrow morning to buy her pearl-and-diamond torsade.
"He never discusses that aspect of his visit," Carol said, "but I know that Mrs, Woodinghurst sold her famous brooch yesterday, and he's agreed to take Maggie Sprenkle's torsade."
Krantz MJ, Kutinsky IB, Robertson AD, et al.: Dose-related effects of methadone on QT prolongation in a series of patients with torsade de pointes.
Magnesium therapy is recommended for patients with ventricular arrhythmia associated with torsade de pointes who present with long QT syndrome as well as for the treatment of patients with digoxin intoxication-induced arrhythmias.
From the sale of the first lot, when an aquamarine torsade necklace estimated at $2,600 fetched more than five times that, it was clear that Princess Salimah, a British-born former fashion model, would not have to worry about money.
Twists or Torsade, threads made of multiple strands of metal twisted together are also sometimes used, some of which, such as Soutache, sometimes have different colored metals or colored non-metal threads twisted together.
Blockade of IKr may lead to excessive prolongation of APD and repolarization instability, which may promote arrhythmic conditions in the heart, including EAD and Torsade de Pointes(TdP).
Before using sotalol, tell your doctor or pharmacist if you have any of the following conditions: certain heart problems (QT prolongation in the EKG, history of torsade de pointes), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).