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There is evidence that other people in the same household as a vaccinee also become relatively protected.
The mechanism of transfer from the vaccinee to the spouse is uncertain.
The vaccinee reported observing all of the standard precautions to avoid household spread.
These registries should be accessible at the local level, as close to the vaccinee as possible.
Furthermore, it is likely that two doses of vaccine will be required to achieve a protective response in the vaccinee.
It is a rare complication of immunization but, even so, it should be anticipated in every vaccinee.
The preponderance of evidence standard under the Vaccine Act requires proof that a vaccine more likely than not caused the vaccinee's injury.
The second case occurred in a woman aged 18 years with no history of smallpox vaccination who handled the bandage of a military vaccinee. Source:
VSD mortality rates demonstrate a healthy vaccinee effect where rates were lowest in the days immediately following vaccination, most apparent in the older age groups.
• Vulvar Vaccinia Infection after Sexual Contact with a Smallpox Vaccinee:
The CDC indicated that it was aware of four similar cases in the preceding 12 months of vaccinia infection after sexual contact with a recent military vaccinee.
To accurately document all information pertaining to each vaccination episode, in the vaccinee's records, Tamariki Ora book and Immunisation Certificate, as appropriate.
Genetic variance among individuals For a vaccine to be effective the vaccinee must be able to recognise and mount an immune response to the vaccine which has been administered.
Given the long incubation period of hepatitis A (2 to 7 weeks), vaccine given a few days after exposure can still elicit an adequate immune response to protect the vaccinee.
The healthy vaccinee effect suggests an avoidance or delay of vaccination when an individual is sick, leading to lower background rates of illness or mortality immediately following vaccination.
The disease should be considered as a possible diagnosis in any vaccinee who presents with a suggestive history, or signs or symptoms of TB, regardless of immunization history.
The major determinant of seroprotection rates achieved is the age at vaccination, but outcome also varies with the schedule used, the dosage and the underlying health status of the vaccinee.
Following 450 million doses over 30 years; there has never been a recorded case of clinical measles, mumps or rubella disease following contact with an MMR-II vaccinee.
Essentially vaccines mimic actual infectious disease causing microorganisms in such a way as to maximise the ability to form an immunity without putting the vaccinee at any substantial risk of contracting the disease.
Concern regarding possible allergy in vaccinee Gastrointestinal intolerance to eggs The inability to eat eggs for reasons other than allergy is not associated with an increase of adverse events to any vaccine.
Canada Communicable Disease Report, Volume 33, ACS-3, 1 May 2007 Vulvar Vaccinia Infection after Sexual Contact with a Smallpox Vaccinee:
The inability to detect sterilizing immunity in high-dose challenge experiments led to a shift of focus towards indirect effects of vaccine candidates on the pathogenicity of the infection and the infectiousness of the vaccinee.
The first case occurred in a woman aged 26 years who slept in the same bed several times a week over a 3-week period with a military vaccinee beginning shortly after he received smallpox vaccine; he reportedly did not always keep his vaccination site covered.
After a first dose of IPV, protecting the vaccinee against central nervous system invasion by wild or vaccine strains of poliovirus, OPV is administered, resulting in an additional protection at the mucosal surface (Kimpen and Ogra, 1990).
Health professionals should be made aware of their responsibility to assess thoroughly any VAAE that is brought to their attention; failing a satisfactory assessment by a health professional, the vaccinee should have available a mechanism for self-reporting to the local health authority.
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