These types of experiments have often been done using traditional embryological non-genetic model organisms, such as the chicken and African clawed frog.

There were visions of tree frogs and giant African frogs powerful enough to knock a man down.

Battelle, for example, is using eggs extracted from the South African clawed frog to test chemicals known to produce birth defects.

One owner imported giant African frogs to compete with the humble local bullfrogs.

When the giant African frogs appeared, everyone thought this years contest was a foregone conclusion.

Between 1930 and 1960, female African clawed frogs were used as pregnancy tests.

"There's an African frog with nasty habits."

It is also known to be one of only three species of African frogs to have claws, used on demand, when it feels threatened.

He keeps his African frogs in a 1,500-gallon pond about 12 feet square, with logs and plants around the perimeter and an island in the center.

"What I remembered first was an African frog."