It is responsible for the coordination of scientific activities as well as for systems operations and life support on board the orbiting Columbus laboratory.

Columbus laboratory is the largest single contribution to the ISS made by the European Space Agency (ESA).

On February 11, 2008, ESA's Columbus laboratory was attached to the starboard hatch of the Harmony module during space shuttle mission STS-122.

The mission was charged with the responsibility of putting the Columbus laboratory in orbit, in addition to its connection to the International Space Station.

Nespoli contributed to the scientific exploitation of Europe's Columbus laboratory.

It consists of a number of modules (primarily the Columbus laboratory) in the US segment, ATV supply ships, launchers, software and €8 billion.

ESA's largest physical contribution has been the Columbus laboratory, launched in 2008.

Biolab is a single-rack multi-user science payload designed for use in the Columbus laboratory of the International Space Station.

Biolab was pre-installed inside the Columbus laboratory.

Since its first use in the Columbus laboratory, the ETC has been used as a transport rack within the multi-purpose logistics module (MPLM).