As Saint Mark's Church has had a long history, there were several occasions upon which there were Papal visits made by different Coptic Popes.

Pope Matthew of Alexandria could mean one of the following Coptic Popes:

The church is the burial place of a few of the Coptic Popes.

Cyrillus is named after Saint Cyril of Alexandria, a 4th-century Coptic Pope and theologian.

By 1646 he was in Cairo, where he seems to have been known at the court of the Coptic Pope of Alexandria.

B3 The Coptic Orthodox Church's Pope was in the New York area to visit his largest religious community outside Egypt.

He was twice nominated to become Coptic Pope, but was not chosen in either case.

Coptic Popes also choose regnal names distinct from their given names.

Pope Andronicus of Alexandria was the Coptic Pope of Alexandria (616-622).

John has been the papal name of several Coptic Popes.