By the time the monks arrived in Constantinople, the political landscape changed and Emperor Justin's policies were directed more to the west than to the east where the Monophysites were dominant.

The schism caused by the Henotikon was officially settled in 519 when Emperor Justin I recognized the excommunication of Acacius and reunited the churches.

Justinian would have, in earlier times, been unable to marry her because of her class, but his uncle Emperor Justin I had passed a law allowing intermarriage between social classes.

Emperor Justin is recorded as receiving John honorably and promised to do everything the embassy asked of him, with the exception of restoring converts from Arianism-to-Catholicism to their original beliefs.

John, exiled by the Monophysites and reinstated by Emperor Justin I in 518.

Outraged, Kaleb, the Christian King of Aksum with the encouragement of the Byzantine Emperor Justin I invaded and annexed Yemen.

It was during this period that the ailing Emperor Justin finally died in early October 578.

On 25 February 520, he was elected bishop by the Byzantine Emperor Justin I, with the consent of bishops, monks, and people.

He went to Constantinople, where he was received by Emperor Justin I, baptized as a Christian, and wedded to a noble wife, Valeriana.

The politics of this is demonstrated by the fact that the Emperor Justin ignored the pope's candidate for the vacated see of Alexandria and instead.