The genetic changes are passed on to the next generation.
Individuals almost never experience genetic change in their own single lifetime.
Therefore, it appears this genetic change is usually required for the development of the disease.
The time scale for evolutionary or genetic change is very long.
The modern era has not existed long enough to cause genetic change.
A small number of children have tumors with genetic changes similar to those found in adult patients.
Although such people most likely do not have an affected parent, they can pass the genetic change to their children.
Of these three effects, only genetic change brings about adaptation.
And they say that despite the progress so far, scientists understand only a minority of the genetic changes involved in cancer.
But so many genetic changes give rise to a question: how does a cell acquire them?