Grapevine Canyon may refer to:

Grapevine Canyon (Kern County, California)

Grapevine Canyon (Death Valley)

Grapevine Canyon (Nevada)

Grapevine Canyon (disambiguation)

Another village was located in Grapevine Canyon near the present site of Scotty's Castle.

The springs of Grapevine Canyon provided the water supply for the ranch and were used to generate electricity.

Another was a smaller parcel near the Interstate - near Grapevine Canyon - that could become a large industrial park.

Past Fort Tejon, the route descends through Grapevine Canyon to Grapevine (named for grapevines in the area).

The 1955 song Hot Rod Lincoln celebrates the long steep and already fairly straight section up Grapevine Canyon.