The HIV-1 protease is an enzyme that cleaves a very large HIV protein into smaller, functional proteins.
In this study, we show that HIV proteins may synergize with drugs such as methamphetamine and cocaine to cause neurotoxicity.
The Western blot test found that antibodies against all nine detectable HIV proteins were present in Rayford's blood.
In subsequent steps, the binding of serum antibodies to specific HIV proteins is visualized.
Some commercially prepared Western blot test kits contain the HIV proteins already on a cellulose acetate strip.
We have designed drugs that target HIV proteins; they severely limit the progression of the disease, and can reverse it in some cases.
HIV proteins gp120 and Tat have been implicated in the neuropathogenesis of HIV dementia.
One possible cause of this acceleration may be the synergistic neurotoxic properties of HIV proteins and the drugs of abuse.
In fact previous studies have shown that most of these substances can be induced by HIV proteins in uninfected monocytes and astrocytes [ 14].
Another HIV protein, Tat, has been demonstrated to suppress T cell activity.