There is a men's and a women's race, the latter called the Liberty Classic.
The $52,000 Liberty Classic for women will be contested simultaneously Sunday over 57.6 miles.
"I am not that tough," she said in an interview last week in Philadelphia, where she was competing in the Liberty Classic.
Despite scrapes and bruises from a four-woman crash near the end of last Sunday's $44,737 Liberty Classic, she finished 25th.
Competed at the same time and over the same course is the women's Liberty Classic.
The $52,000, 57.6-mile Liberty Classic for women will be run over the same course.
A women's race, the Liberty Classic, over 58 miles and worth $43,860, will open the festivities on Sunday.
A four-time participant of the women's Tour de France, Hughes has won the 1994 Women's Challenge and the 1997 Liberty Classic.
The Liberty Classic is an annual women's bicycle race held since 1994 simultaneously with the Philadelphia International Championship.
The Liberty Classic is the final leg of the inaugural 2006 Commerce Bank Triple Crown of Cycling for women.