Over time, these changes, or mutations, lead to new species.

These mutations can lead to various diseases at the tissue level.

On rare occasions, however, further mutations can lead to new varieties.

Mutations may lead to decreased or increased activity of enzymes.

Thus, a mutation leads to an increased susceptibility to cancer.

Researchers have identified why a mutation in a particular gene can lead to obesity.

This extreme mutation leads to the death of the organism.

Then, mutations would lead to cellular dysplasia and to cancer.

The mutation leads to change in the transcript level equilibrium.

Spetner claims mutations lead to a loss of genetic information.