The Seneca River forms the north border and Onondaga Creek formed part of the eastern boundary.

Onondaga Creek contributes approximately 30% of the hydrological input to Onondaga Lake.

At its mouth, Onondaga Creek is enriched with nutrients and suspended sediment.

Onondaga Creek runs through the area to the west and Interstate 81 borders the area to the east.

The nation has accused the mine of polluting the Onondaga Creek, which runs into the lake.

The sediment from the mudboils enters Onondaga Creek which flows north into the lake.

It served to address sewage-related problems in Onondaga Creek and Harbor Brook.

In 1720, it was moved to Onondaga Creek.

American troops methodically destroyed the abandoned settlement, razing about 50 houses along Onondaga Creek.

Onondaga Creek, a waterway that runs through downtown, flows northward through the city.