Their function was and remains unclear, though they were not thought to be associated with active DNA replication, transcription, or RNA processing.
Extensive RNA processing may be an evolutionary advantage made possible by the nucleus of eukaryotes.
There are also non-coding RNAs involved in gene regulation, RNA processing and other roles.
Trans-splicing is a form of RNA processing.
The process of transcriptional termination is less well understood in eukaryotes, which have extensive post-transcriptional RNA processing.
Second, there can be a bend in the DNA that will inhibit RNA processing.
Since RNA processing is heritable, it is subject to natural selection and contributes to the evolution and diversity of most eukaryotic organisms.
On the whole, RNA processing expands the possible phenotypes of a given genotype and contributes to the evolution and diversity of life.
Virtually any step of gene expression can be modulated, from transcriptional initiation, to RNA processing, and to the post-translational modification of a protein.
Lack of correct ribosomal RNA processing is lethal to cells, explaining the antimetabolic effect of the drug.