Prior to 1926, what is now US 10 was State Trunk Highway 18.

However, Highway 18 initially (in 1917) only ran from Humbird, near where US 10 and U.S. Highway 12 (then State Trunk Highway 12) cross, east to Manitowoc.

State Trunk Highway 34 ran from Prescott to Highway 37 in Mondovi.

With the completion of State Trunk Highway 441 in 1993, the area gained easier access to the rest of the Fox Cities.

State Trunk Highway 119 has had many different versions throughout different areas of Wisconsin.

State Trunk Highway 310 (often called Highway 310 or simply 310) is a state highway in the U.S. state of Wisconsin.

State Trunk Highway 11 (often called Highway 11, STH 11 or WIS 11) is a state highway running east-west across southern Wisconsin.

Prior to the commissioning of Interstate 43 in the early 1970s, the current route of WIS 142 was designated as State Trunk Highway 43 (WIS 43).

State Trunk Highway (often called Highway 194, STH-194 or WIS 194) was a state highway in the U.S. state of Wisconsin.

State Trunk Highway 100 (STH 100, commonly known as Highway 100 or WIS 100) is a road which encircles the outer edges of Milwaukee County.