With few exceptions, the abuse liability observed in rats paralleled that observed from previous research in monkeys.
Such a side-effect profile is thought to give ethanolamine-class antihistamines a relatively low abuse liability.
The results of animal experiments conducted with this drug suggest that it has an abuse liability similar to cocaine and amphetamine.
Nitrazepam was found to be an abusable drug and has similar abuse liability like diazepam, if not slightly higher in these drug abusers.
He said the drug should have "absolutely no abuse liability whatsoever."
Its abuse liability is similar to morphine and less than oxycodone.
A 1991 study indicated that diazepam, in particular, had a greater abuse liability among people who were drug abusers than did many of the other benzodiazepines.
The abuse liability of dronabinol (delta-9-tetrahydrocannabinol) is expected to remain very low so long as cannabis continues to be readily available.
The Committee considered that the abuse liability of dronabinol does not constitute a substantial risk to public health and society.
Since these agonists function as reinforcers, there is an obvious concern surrounding their abuse liability.