The actual choice of drug is not as important as an adequate dose and the child's and parents' compliance with the treatment regimen.
However, treatment resistance is widely defined as lack of therapeutic response to two antidepressants at adequate doses for an adequate duration and with good compliance.
It would seem so reasonable to define pain as that verbal response or any other sign which disappears if an adequate dose of morphine is administered.
A year later, the same journal published research confirming that adequate doses of amphetamine could boost performances in runners and swimmers.
Similarly, tranylcypromine has been shown to completely suppress REM sleep at adequate doses.
An adequate dose of hemodialysis should result in an average URR of 65%.
An adequate dose of hemodialysis should result in an average Kt/V of 1.2.
An adequate dose of dialysis can usually be delivered in 3 to 5 hours.
Children whose growth has been delayed because of hypothyroidism start growing normally again once they get adequate doses of thyroid hormone.
But with digitalis, the margin between an adequate dose and overdose is usually very narrow.