It mainly affects dopamine D, serotonin 5-HT and α-adrenergic receptors.

Intuniv affects certain receptors in the brain and also improves concentration and impulse control.

In vertebrates such as mice, they are known to affect opioid receptors resulting in elicitation of naloxone-sensitive antinociception and reduction of morphine-induced antinociception.

Currently, naltrexone takes more of a buckshot approach, affecting multiple receptors.

However, because these chemical drugs directly affect natural chemical reactions and receptors in the body, the ethics of their use as well as safety are in question.

Guanfacine is thought to affect receptors in the parts of the brain that lead to strengthening working memory, reducing distraction, and improving attention and impulse control.

A great number of drugs are available which can affect adrenergic receptors.

This study suggested that intrauterine infections in the mother could affect glial cells and toll-like receptors (TLRs) which are important in moderating the inflammatory response in the fetal brain.

It looked very promising in in vitro trials proving to be a potent competitive antagonist at the NMDA without affecting other receptors.

Researchers at the University of Florence showed that furanoeudesma-1,3-diene and another terpene in the myrrh affect opioid receptors in the mouse's brain which influence pain perception.