Against Gladden's instincts to stay in the city but he couldn't leave just yet.

You've probably done things or gone out with people against your best instincts.

It was against his natural instincts, but he stepped away.

Just shows what happens when you go against your instincts.

None was working against its basic instincts, but with each bird she had created something more.

This was a case where workers should have been protected against their own destructive instincts.

Wendy nods, but I can see it goes against her instincts.

Against our better instincts, we think, "Go with this nice older man."

I could give you case studies, Eve, but they wouldn't hold up against your instincts.

Which means I've become a scientist, against all my better instincts.