So, all possible peptides with proline at 2 and tyrosine at 8 or 10, as well as their allelic variants, were also tested.
Similarly, genetic association studies between allelic variants of the resistin gene and metabolic abnormalities have so far been inconclusive.
For instance, the influence of the CYP2D6*1/*4 allelic variant on the clinical outcome in patients treated with Tamoxifen remains debated today.
An allele is subject to negative frequency dependent selection if a rare allelic variant has a selective advantage.
The possibility of allelic variants of A1AT leading to disease was first investigated by Axelsson and Laurell in 1965.
There are 5 identified allelic variants responsible for LEOPARD syndrome.
The human population has both functionally inactive hAOX1 allelic variants and encoding enzyme variants with different catalytic activities.
Subjects possessing certain allelic variants will show normal, decreased, or no CYP2D6 function, depending on the allele.
The mutations have not been studied as much as PSEN1, but distinct allelic variants have been identified.
The gene is associated with allelic variants.