Group marathon training is expanding across the country and running groups, health clubs, coaches and personal trainers are becoming instrumental in providing safe and successful venues for long-distance training.

Originally established to fulfill the legal requirements of a nonprofit entity, boards have become increasingly instrumental to the theaters, both as fund-raisers and as official links to the community.

Their contributions to music, art, language, and heritage have become instrumental to Puerto Rican culture.

The charity also serves as an advocate for teenage cancer needs, becoming instrumental in the establishment of related research and national and international forums.

Interdealer brokers play varying roles in each of the fixed income markets and have become instrumental to their effectiveness and efficiency.

Much of modern slack-key guitar has become entirely instrumental.

Doop was said to be the product of a Cold War era U.S. military experiment, becoming instrumental in the fall of the Soviet Union.

Laboratory automation, therefore, has become instrumental to the progress of the life sciences.

Are our close ties becoming shallower and more instrumental?

Another reason is that peptides have become instrumental in mass spectrometry, allowing the identification of proteins of interest based on peptide masses and sequence.