"The really big message here is that women need to know their risk," he added.

I think there's a big message of hope right now because before there was no way to get over this.

Well the great thing we were able to do at this briefing is, I think, deliver on three big messages.

So I guess the biggest message is that you have to be patient.

This is probably the novel's big message, too, because, really, what else could it be?

"I don't think you can send us a bigger message than we have got."

Difference is the biggest message they must send to the world.

"To me the big message is that we now have both and we do not need to wait any longer."

Or, for a smaller present with a big message, how about a simple pair of Flexicuffs?

What's the big message and why did you call us over here?