The problem of explaining the mind is so complex as to require "big science" to make real progress.
"But that has nothing to do with big science," he says.
There is no evidence that the money now going into big science would have been available for more traditional uses.
The second occupational hazard of big science is catastrophic failure.
But Washington has now committed itself to spend at least $60 billion on big science in this decade.
"We're freezing out a lot of our good work because of the commitment to big science."
The Administration is seeking increased funds as the main way of achieving its goals for both big and little science.
Scientists themselves are not blameless in the push for big science.
Such conflicts have grown in recent years as big science has flourished.
From the beginning such instrumentation bore the mark of big science.