"It would be a big setback, a waste of the summer, if we don't win that game."
The biggest setback by the board involved the rape scene.
As such, the ruling is a big setback for Microsoft.
He experienced many physical changes, making him an even bigger setback in Victor's future plans.
Our relationship had suffered a big setback and I was disappointed.
The decision was a big setback for the insurers, which have won similar cases in the past.
But the biggest setback may be the loss of international aid.
It enjoyed great commercial success, but not without one or two big setbacks.
The stock market suffered its biggest setback in seven months.
But for every small advance of the new technology, there are bigger setbacks.