At least one of the genes is involved with the production of a normal brain protein called amyloid.
The researchers say they have bred mice missing a gene that bears instructions for making an important brain protein.
He said this was the first time that a brain protein from chromosome 21 had been found.
The normal prion is a healthy brain protein that may play a role in nerve signaling.
Scientists have found a brain protein that they say could be the "smoking gun" in deaths due to Huntington's disease.
They essentially put thousands of brain proteins inside yeast and mixed them with the huntingtin protein.
It was a brain protein that binds only to huntingtin.
Four of the brain proteins looked the same in all the teenagers, Dr. Phillips said.
The mouse ortholog is called brain protein 17 (Brp17).
Since the foreign proteins are so similar to normal brain proteins, they presumably slip through the immune system's net.