But his life and career have been blighted by drink, alcohol and depression.

When he began to record again, his voice was low, sluggish, once more crushed flat by depression.

The street has become characterised by dereliction & economic depression.

With little medical knowledge, and often burdened by fear, depression or pain, hospitalized patients can have a hard time properly weighing their options.

This was their world - dark, stormy, torn by depression and war.

Though clearly all but paralyzed by depression now, she still makes a reflexive, ineffective attempt to tidy her hair.

He was under siege by drink, deafness and depression.

Eventually, she found the fortitude to leave him, though she still felt consumed by depression.

No one should feel embarrassed or stigmatized by depression.

New medicines can also control arthritis associated with the illness and help people cope, for example, by easing depression, he said.