How could such a simple thing have catastrophic effects on the history of two worlds?

But a few patients have a deficit in the process of healing which could lead to catastrophic effects.

The power crisis has had catastrophic effects on the economy.

This last event had a catastrophic effect on the Shah.

No mention of the catastrophic effects on the environment all these gadgets have.

It is quite likely to cause unpredictable and possibly catastrophic side effects.

Their skills are used to catastrophic effect in war.

Many scientists believe this could have a catastrophic effect on climate.

They are counterproductive and have catastrophic effects on Iraq's civilian population, above all for children.

This is a catastrophic effect which almost inevitably leads to failure.