Early radiation effects usually are related to a significant fraction of cell loss that exceeds the threshold for impairment of function in a tissue.
An increased cell loss during incubation with BrdU as another possible explanation is not supported by published works.
"The dire picture we've had of huge cell losses is wrong for a healthy person whose brain remains structurally intact into old age."
Biochemical analyses were employed to verify whether or not cell loss was the result of apoptosis.
Neurodegenerative disorders are characterized by progressive cell loss in specific neuronal populations.
The chronic response occurs when the initial increase in cell proliferation fails to compensate for the cell loss.
However, because such cell loss occurs in other eye diseases, the disorder cannot be diagnosed by this sign alone.
It occurs because of progressive cell loss in numerous sites in the central nervous system.
Why this cell loss occurs is unknown.
But it is the area where cell loss occurs in Alzheimer's patients, so its importance is real.