He seemed under a chronic irritation of the greatest intensity.

It is the mouth's reaction to chronic irritation of the mucous membranes of the mouth.

Repeated or prolonged inhalation of vapors may lead to chronic respiratory irritation.

This, in turn, causes chronic irritation and gradually malignancy may develop in the skin at the waistline.

The eye is also a source of chronic irritation.

Eczema is another cause of chronic irritation and affects millions of individuals.

This disorder is associated with chronic irritation under folds of skin.

Dry skin, chronic irritation, eczema and psoriasis are possible causes of neurodermatitis.

Persistent stress can lead to chronic irritation and inflammation of the bone covering and adjacent tissues.