But the clinical significance of the changes is not clear.

The clinical significance of this has yet to be determined.

"Other than the pain, it is of no clinical significance," he said.

There are no data to indicate that this effect is of clinical significance.

But he said the clinical significance was likely to be minimal.

This is a major factor in the clinical significance of disease.

The clinical significance of these findings, if any, is unknown.

Some sources consider them to be of no clinical significance.

The clinical significance of this protein has not been established.

We need more research to find out if there is any real clinical significance.