Overdiagnosed disease is a neoplasm that would never become clinically apparent prior to a patient's death without screening.
With the introduction of antithyroid drugs and radioiodine in the 1940s, clinically apparent hyperthyroid bone disease became less common.
Mammography is picking up many early cancers that might not have become clinically apparent for several years.
"A lot of what we're calling disease now never becomes clinically apparent during the life of the patient," he said.
No patient developed clinically apparent neuromuscular transmission blockade.
Only about 30/-40% of patients with hepatitis B develop clinically apparent acute hepatitis.
No clinically apparent mucosal involvement is present even with widespread disease.
Such an approach is vital with the increasing demands being placed on health professionals to detect and treat disease before it is clinically apparent.
Most clinically apparent miscarriages (two thirds to three-quarters in various studies) occur during the first trimester.
If untreated, these "asymptomatic" infants can develop clinically apparent disease in the ensuing 3 weeks to 6 months.