They may also be involved in hearing impairment via cochlear damage induced by noise health effects, ototoxicity of drugs such as cisplatin, and in congenital deafness in both animals and humans.

Autoimmune disease has only recently been recognized as a potential cause for cochlear damage.

There are auditory nerve fibers connecting this high frequency region to corresponding auditory cortex in the brain, and the firing rates of this auditory nerve fibers in high frequency region significantly decreases due to cochlear damage.

Attenuation of aminoglycoside-induced cochlear damage with the metabolic antioxidant alpha-lipoic acid.

In their review of localisation and lateralisation studies, Durlach, Thompson, and Colburn (1981),cited in Moore (1996) found a "clear trend for poor localization and lateralization in people with unilateral or asymmetrical cochlear damage."

NIHL caused by acoustic trauma refers to permanent cochlear damage from a one-time exposure to excessive sound pressure.

Gradually developing NIHL refers to permanent cochlear damage from repeated exposure to loud sounds over a period of time.

Due to the difference in the function of these structures, ototoxic poisoning affects the patient differently than in the case of cochlear damage.

Symptoms present similar to those resulting from vestibular and cochlear damage, including tinnitus, ringing of the ears, difficultly walking, deafness, and balance and orientation issues.