Alexander's presence on this ship had been a constant irritation.

The constant irritation results in excess production of mucus which makes breathing difficult.

This is your body's natural response to constant irritation.

Rick suspected that it was a nervous habit, the eye red only because of constant irritation.

His temper was in a state of constant irritation.

If the Tuatha'an camp was a source of constant irritation, at least his dreams were normal there.

"A teacher is a constant irritation; and the worth of a man is God."

Nothing to turn out the guards for, but constant irritations, like burrs caught in the skin.

These new lights are a constant irritation to him and he angrily bats them away at times.

It is the crucial grain of constant irritation around which his depraved politics have been allowed to form.